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Manganese – Mastering Minerals Series 1

InterClinical eNews February 2020, Issue 101 In this issue we examine one of the lesser known nutrients, Manganese. Although this is a trace element and is needed by the body in very small quantities, it is critical for good health. What is manganese’s role in good health? How do we know when to prescribe it? ‘A well-known professional basketball player was a devout vegetarian. He felt he performed better if he kept...

Pyrrroluria medical condition or biomarker

Pyrroluria  -  Medical Condition or Biomarker?

InterClinical eNews March 2019, Issue 90 This month's issue explores the evidence for Pyrroluria, and asks the question - is it a discrete medical condition or is it a biomarker of other pathology? We take a look into the history, research findings and treatment options.  Detection  Hydroxyhemopyrrolin-2-one (HPL) or "mauve factor" was first discovered in 1958 in the urine Dr Hoffer's psychiatric patients. It was named after the colour it appeared in chromatograph assays. It was later identified by a fellow researcher, Irvine, as...

Copper Deficiency Anaemia

Anaemia and the Copper-Deficient Patient

InterClinical eNews November 2018, Issue 86 Copper deficiency is a less common and under-recognised cause of anaemia, producing an anaemia unresponsive to iron, vitamin B12 or folate. In this journal article four expert reviewers highlight the key features, the likely causes, the populations affected and how to treat the symptoms.Copper Deficiency Symptoms Mild copper deficiency is largely indistinguishable from other types of anaemia, apart from a persistent neutropenia. As it progresses in severity the symptom picture becomes...